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mavorixafor will improve the amount or result of codeine by impacting hepatic enzyme CYP2D6 metabolism. Contraindicated. Mavorixafor (a strong CYP2D6 inhibitor) is contraindicated with drugs that are remarkably depending on CYP2D6 for clearance.
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clozapine decreases results of codeine by affecting hepatic enzyme CYP2D6 metabolism. Use Warning/Monitor. Prevents conversion of codeine to its Energetic metabolite morphine.
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Health care suppliers should decide on most affordable successful dose for shortest length of time and advise people and caregivers about these hazards and indications of opioid overdose
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